Interview With Dr. Zach Bush – SARS CoV2 – ACE2 Receptors

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Who is Dr. Zach Bush?

“Zach Bush, MD is one of the few triple board-certified physicians in the country – with expertise in Internal Medicine, Endocrinology and Metabolism, and Hospice/Palliative care.”

What is a CoV or Coronavirus?

“CoVs (Coronavirus) are a large family of enveloped, positive-sense, single-stranded RNA viruses that infect a broad range of vertebrates. They are extensive in bats but can be found in many other birds and mammals including humans. CoVs can cause a variety of diseases such as enteritis in pigs and cows and upper respiratory disease in chickens. In humans, CoVs tend to cause mild to moderate upper respiratory tract infections such as the common cold. However, in the past couple of decades, there have been outbreaks of severe, and sometimes fatal, respiratory illnesses that were later found to be caused by novel, human pathogenic CoVs. These CoV strains, which were determined to be phylogenetically distinct from the common human CoVs, had originated in bats and were transmitted to humans, typically through an intermediate host. These strains exhibited stronger virulence and quickly passed from human to human. While infection with these CoVs typically produced mild symptoms, for certain individuals, responses were more severe. In extreme cases, death occurred due to gradual respiratory failure as the result of alveolar damage.” (Source: R&D Systems – Tools for Coronavirus research)

What is SARS CoV2?

Severe Acute Respiratory Syndrome Coronavirus 2 – This is a Novel Coronavirus and in close relationship to the original SARS CoV virus from 2002/03. (Source:  Harvard Magazine)

What is COVID-19?

Coronavirus Disease 2019 or COVID-19 is the formal name of the disease presented in a person who had been infected with the SARS CoV2 virus. (Source:  Harvard Magazine)

How does a human become infected with the SARS CoV2 virus?

Scientists, Doctors and Public Health have known for many years that Coronaviruses of many types including SARS (original from 2002), infect human cells through the ACE2 Receptor.  

“MICHAEL FARZAN ’82, Ph.D. ’97, who in 2002 was an assistant professor of microbiology and molecular genetics at Harvard Medical School (HMS) studying the mechanism that viruses use to enter cells, was the first person to identify the receptor that SARS used to bind and infect human cells. “SARS-CoV-2 is a close cousin to SARS, and uses the same human receptor, ACE2,” reports Farzan, who is now co-chair of the department of immunology and microbiology at Scripps Research. The ACE2 receptor is expressed almost exclusively in the lungs, gastrointestinal tract, and the kidneys, which explains why the disease is so effectively transmitted via both the respiratory and fecal-oral routes.” (Source:  Harvard Magazine)

Human cell infection of SARS CoV2 Coronavirus through the ACE2 receptor (Source: R&D Systems)

Why is the SARS CoV2 cell infection by means of the ACE2 receptor important when looking at the death rate of the presenting disease COVID-19?

The vast majority of deaths around the world are in the age group 65+ with approx. 90% or more of all cases being age 80+.  This has been consistent in European countries like Italy and Spain as well as in the USA and Canada.  The vast majority of deaths in Ontario, Canada for example are age 65+ and in nursing / long term care home outbreaks.

What are some common denominators in this age group?

  1. Many elderly people in the 60+ age range are taking drugs for cardiovascular issues and diabetes that include Statins & Ace Inhibitors.  
  2. In the last year many elderly in our nursing / old age homes / long term care homes have received a new High Dose Influenza Vaccine (Flu Shot) with up to 4x the Antigens compared with a regular flu shot. 

Why are those two points above important to high presentation of COVID 19 in the elderly and the resulting high rate of death in this age group?

Dr. Zach Bush alleges that both the Statin / Ace Inhibitors and the Influenza Vaccines make a person more susceptible to infection from the SARS CoV2 virus and it’s presenting disease COVID 19.  Watch and decide for yourself.

The video above is a clip from Del Bigtree – The Highwire – CORONAVIRUS: THE GREAT AWAKENING – Streamed live on May 7, 2020

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